An infant with disseminated bacillus Calmette-Guerin infection (BCGitis)

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Disseminated Bacille Calmette-Guerin (BCG) disease in an infant with severe combined immunodeficiency.

Bacille Calmette-Guerin (BCG) vaccine is administered to all newborns in countries where tuberculosis is still endemic. It is a live attenuated vaccine and considered quite safe in immunocompetent children. Disseminated BCG disease is the most serious complication seen only in individuals with underlying primary or secondary immunodeficiencies. We report a case of disseminated BCG disease in an...

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Disseminated Bacillus Calmette-Guérin Infection and Immunodeficiency

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Post-Vaccination Disseminated Bacillus Calmette Guerin Infection Among Children in Southern Iran.

BACKGROUND Disseminated bacillus calmette guerin (BCG) infection is a rare but life threatening complication of BCG vaccination. It has been mainly seen in severe immune deficiency. A precise and rapid diagnosis is crucial for prompt initiation of an aggressive anti-mycobacterial treatment. Polymerase chain reaction (PCR) is directly applicable to smear-positive clinical specimens, proven to be...

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post-vaccination disseminated bacillus calmette guerin infection among children in southern iran

conclusions disseminated bcg infection should be considered in the differential diagnosis of infants and young children with fever, hepatosplenomegaly, lymphadenopathy, and history of bcg vaccination. the pcr method has a high positivity rate and can serve as a useful tool for the rapid and specific identification of m. bovis bcg substrain infection. results from the total of 34 children hospit...

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The bone scan pattern in disseminated BCGitis

Despite the long history of the worldwide use of Bacillus Calmette-Guerin (BCG) vaccine, a wide spectrum of adverse reactions has been observed in a small proportion of immunized infants; the most severe complication, disseminated BCGitis, is often fatal but exceedingly rare and is considered to result from host immunodeficiency. At present, CT scan, ultrasound, X-ray and bone marrow aspi...

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ژورنال

عنوان ژورنال: International Journal of Pediatrics and Adolescent Medicine

سال: 2014

ISSN: 2352-6467

DOI: 10.1016/j.ijpam.2014.11.005